CFAR

Status

Study short name

EarlyNuts

Study full name

Can early introduction of dietary allergen reduce the prevalence of infant food allergy? The EarlyNuts population-based study

Principle Investigator

Jennifer Koplin

Administering Institute

Murdoch Children’s Research Institute

Major funding source

National Health and Medical Research Council (NHMRC)

Study focus

Prevention

Study design

Observational

Main study aim

A population-based cross-sectional study of age at the introduction of allergenic foods and food allergy in infants.

Additional study information

Australia has among the highest reported rates of childhood food allergy, a potentially life-threatening condition. New evidence shows that earlier introduction of allergenic foods (like peanut) can reduce the risk of food allergy. This is reflected in new infant feeding guidelines. This study will measure current infant feeding practices and whether earlier allergen consumption has reduced the rate of food allergy in the population. Results will inform strategies to improve uptake and efficacy of timely allergen introduction for food allergy prevention.

Study population

12 month old infants. Participants were recruited from randomly selected council-led immunisation centres across Melbourne on the day of their 12 month immunisation.

Study status

Recruitment completed November 2019. Data collection completed January 2020.

Study contact: [email protected]

Australia New Zealand Clinical Trials Registry: https://www.australianclinicaltrials.gov.au/anzctr/trial/ACTRN12618001990213

Main Publication(s):

  1. Soriano VX, Peters RL, Ponsonby AL, Dharmage SC, Perrett KP, Field MJ, et al. Earlier ingestion of peanut after changes to infant feeding guidelines: The EarlyNuts studyJournal of Allergy & Clinical Immunology. 2019;08:08. doi: https://doi.org/10.1016/j.jaci.2019.07.032.