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HealthNuts

Status

  • Recruitment Closed

Study short name

HealthNuts

Study full name

Population prevalence and environmental/genetic predictors of food allergy in an infant cohort

Principle Investigator

Jennifer Koplin

Administering Institute

Murdoch Children’s Research Institute

Major funding source

National Health and Medical Research Council (NHMRC)

Study focus

Prevention

Study design

Observational

Main study aim

To examine the natural history of allergic disorders including food allergy, asthma, eczema and allergic rhinitis and the interplay of risk factors for development of these conditions in childhood.

Additional study information

The rise in food allergy in developed countries has attracted international scientific attention with Australia reporting the highest rate of both food allergy and food-induced anaphylaxis. The HealthNuts study is the world’s first comprehensive population-based study of food allergy with objective measurement of true food allergy and will enable us to understand better the natural history of allergic disorders including food allergy, asthma, eczema and allergic rhinitis and the interplay of risk factors for development of these conditions in childhood. The study will have important implications for clinical guidelines and public health policy.

Study population

The HealthNuts study recruited 12-month-old infants via their parents/guardians at childhood immunization sessions across the city of Melbourne, Australia. Further follow up occurred at 4, 6 and 10 years of age.

Study status

Recruitment completed January 2011. Data collection ongoing, through December 2019.

Study contact: [email protected]

Study website: www.mcri.edu.au/healthnuts

Main Publications: All HealthNuts Publications

  1. Osborne NJ, Koplin JJ, Martin PE, Gurrin LC, Lowe AJ, Matheson MC, et al. Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants. Journal of Allergy & Clinical Immunology. 2011;127(3):668-676 e661-662. doi: https://doi.org/10.1016/j.jaci.2011.01.039.

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