MIS BAIR (Melbourne Infant Study: BCG for Allergy & Infection Reduction)
A randomised, controlled trial to determine if BCG immunisation at birth prevents the development of allergy & infection in infants
Murdoch Children’s Research Institute
National Health and Medical Research Council (NHMRC), Royal Children’s Hospital Foundation, University of Melbourne and Murdoch Children’s Research Institute
To assess whether the BCG vaccine will prevent food allergy, eczema and lower respiratory tract infections in the first 5 years of life.
Study participants randomised to group 1 received a single 0.05 mL intradermal injection of BCG Vaccine SSI or BCG 10 Vaccine over the distal insertion of the deltoid muscle onto the humerus approximately one third down the upper left arm.
1272 healthy newborns randomised in the first 10 days of life.
Recruitment completed September 2016. Data collection ongoing, through February 2022.