CFAR

Status

How to participate

If you are interested in participating in this study, please visit the SYMBA study website for more information.

Study short name

SYMBA

Study full name

Dietary modulation of maternal gut flora with oligosaccharides in pregnancy as a novel allergy prevention strategy

Principle Investigator

Susan Prescott

Administering Institute

Telethon Kids Institute

Major funding source

National Health and Medical Research Council (NHMRC)

Study focus

Prevention

Study design

Intervention

Main study aim

To determine whether maternal prebiotic supplementation during pregnancy and breastfeeding can reduce the development of eczema in babies.

Additional study information

Prebiotics are a type of fibre that occur naturally in foods such as whole grains, vegetables and legumes. They are called ‘prebiotics’ because they are digested by gut bacteria, but are different from ‘probiotics’ which are the actual ‘friendly bacteria’. Participating women will be asked to consume a prebiotic or placebo powder daily, from mid-pregnancy until their baby is 6 months old.

Study population

Pregnant women, less than 21 weeks gestation, whose baby-to-be has a mother, father or sibling with a history of medically diagnosed allergic disease (asthma, allergic rhinitis, eczema and/or food allergy).

Study status

Recruitment ongoing, through March 2021.