A phase 2, dual-centre, randomised, controlled trial evaluating the effectiveness of probiotic and egg oral immunotherapy at inducing desensitisation or sustained unresponsiveness (remission) in participants with egg allergy compared with placebo (Probiotic Egg Allergen Oral Immunotherapy for Treatment of Egg Allergy: PEAT study).
Murdoch Children’s Research Institute
National Health and Medical Research Council (NHMRC)
The aim of the study is to test the hypothesis that probiotic and egg OIT is more effective than placebo at inducing sustained unresponsiveness (remission) in participants with egg allergy 8 weeks after end-of-treatment.
This is a randomised, placebo-controlled trial investigating whether probiotic given in combination with egg OIT is effective at inducing sustained unresponsiveness in egg allergic children.
The participants in this study are aged between 5 and 17 years old at time of enrolment. Participants are allergic to egg, and may have additional food allergies.
17 June 2021
Study contact: [email protected]
Study Recruitment Information: PEAT Recruitment Flyer
Australia New Zealand Clinical Trials Registry: https://www.australianclinicaltrials.gov.au/anzctr/trial/ACTRN12619000480189p